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Compared with oral administration or the extremely difficult intra-articular injection into small joints, MNs offered a minimally invasive, painless transdermal drug delivery system

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Allergy (2009) 64(10):15249

Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage

And for patients who do eventually have surgery, GLP-1s are increasingly part of the picture before and after

For nausea, smaller meals, eating more slowly, and avoiding heavy or high-fat foods, especially early in treatment, are often helpful