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Randomized, placebo controlled, double-blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoaging of facial skin

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The effect may appear within 4560 minutes after administration and can last for several hours

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However, abnormal wound healing processes caused by deep trauma or chronic inflammation resulting from genetic and environmental factors disrupt this homeostatic network, leading to intractable skin diseases, such as pathological scars and atopic dermatitis (AD) (Weidinger and Novak 2016