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12 Nicotine also affects the development of brain circuits that control attention and learning

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Its true that we cannot say that iQOS is less harmful than normal cigarettes

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The authors state that their findings should prompt extra efforts to prevent smoking experimentation and/or initiation earlier in the life course given that it appears to be critically related to more unbreakable lifelong smoking patterns. It is not clear why smokers with an earlier and more-intense smoking history tend to become daily smokers and have a harder time quitting, they said, but it may be due to early exposure to nicotine