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AATS, 2011
Glutathione, often referred to as the master antioxidant, is a naturally occurring molecule made up of three amino acids: glutamine, cysteine, and glycine
Neuroimmune communication via calcitonin gene-related peptide (CGRP) and its coreceptor RAMP1 promotes macrophage recruitment and phenotypic shifts toward a pro-endometriosis state, characterized by impaired efferocytosis and enhanced support of endometrial cell growth ( Natural killer (NK) cell function is severely compromised, with reduced cytotoxicity of the CD56dimCD16+ subset in peripheral blood and peritoneal fluid, enabling immune escape of ectopic cells ( T-cell subsets are dysregulated, with increased Th2, Th17, and regulatory T (Treg) cells in the peritoneal microenvironment ( 2.2.2 Immune checkpoint molecules Immune checkpoint pathways are perturbed, contributing to immunosuppression
McMahon CJ, Hopkins S, Vail A, King AT, Smith D, Illingworth KJ, et al
E., & Porges, E
In addition to being an antioxidant itself, glutathione is also a cofactor for several other antioxidant enzymes1-3
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