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Decreased branched-chain amino acid (BCAA) levels in serum of patients with RA were observed in another study 37

The treatment group saw a significant reduction in mean AHI from 50 32 to 38 30 ( p = 0.0002), with 70% of participants experiencing at least a 44% reduction

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DOSING USED IN PHASE 3 STUDIES In the most recent studies from the TRIUMPH programme (Phase 3) , retatrutide was administered as follows: Route: Subcutaneous Frequency: Once weekly Study duration: Approximately 68 weeks Recommended Dosage (Clinical Research Escalation Model) Retatrutide is administered once weekly using a gradual dose escalation to improve tolerability