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This doesn't mean you can never take ibuprofen, but frequent or high-dose NSAID use during your weight loss journey could undermine your results

Never discontinue or adjust your medication without medical guidance

The first week I lost 10 pounds

Weight loss from semaglutide can impact your cycle, but missed periods , spotting, and increased bleeding might also indicate a health problem like PCOS or polyps

Systemic symptoms : Fever, chills, malaise, or other systemic symptoms accompanying injection site reactions require medical assessment to rule out infection or hypersensitivity reactions

As of early 2025, there are no completed clinical trials specifically evaluating tirzepatide for Alzheimer's disease prevention or treatment, as confirmed by searches on ClinicalTrials.gov