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Overlap between GLP1RA-related metabolites We found that metabolites shared between analyzed GLP1RA networks are associated with Galactose metabolism (ATP, ADP, alpha-D-Glucose, D-Fructose, D-Glucose, Glucose 6-phosphate, Pyrophosphate, Sucrose, Water), neomycin, kanamycin and gentamicin biosynthesis, starch and sucrose metabolism, arginine and proline metabolism but also nitric oxide-related pathways, platelet homeostasis (ATP, ADP, citrulline, cyclic GMP, guanosine triphosphate, hydrogen ion, L-arginine, NADPH, nitric oxide, oxygen, pyrophosphate) and VEGF-related pathways (ATP, ADP, citrulline, guanosine triphosphate, hydrogen ion, L-arginine, NADPH, nitric oxide, oxygen)

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The key changes: TRICARE For Life beneficiaries: No longer eligible for weight loss medication coverage Revised prior authorization criteria: Updated clinical criteria with more specific documentation requirements No military pharmacy fills: Weight loss drugs can no longer be filled at military pharmacies TRICARE Prime and Select: Coverage continues with prior authorization Wegovy vs

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