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10.1016/j.neuron.2007.07.025 Neuron 81 ParkK.LeeJ.JangH

MTX treatment resulted in obvious toxicity as early as 18 days after induction, with increased levels of alkaline phosphatase (AKP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), uric acid (UA), blood urea nitrogen (BUN), and creatinine (CRE) reinforced on day 35, and probably induced by glycolysis-facilitated intestinal absorption (170)

Personal medical decisions should involve a licensed clinician

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They have a lower dose (60mg) than prescription versions like generic/unbranded orlistat and Xenical (120mg), so you dont need a prescription, but a pharmacist will check if its suitable for you