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Choline may increase cholinergic tone and could theoretically augment adverse reactions when combined with acetylcholinesterase inhibitors such as donepezil

In general, consistent with preclinical studies, RSV supplementation (500 mg/day, P.O for 4 weeks) raised erythrocyte PPAR- and Sirt1 expression and serum TAC and attenuated the total/HDL cholesterol ratio in CHD patients with type 2 diabetes [198]