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[9] [10] Several factors may explain why some individuals experience fatigue whilst taking GLP-1 medications: Reduced caloric intake : The appetite-suppressing effects can lead to significantly lower food consumption, potentially resulting in inadequate energy intake, particularly if patients are not consuming balanced, nutrient-dense meals

Rosiglitazone-associated fractures in type 2 diabetes: an analysis from A Diabetes Outcome Progression Trial (ADOPT) Diabetes Care

And even among those who do experience those side effects, they are usually both minimal and temporary, says Knopke

GLP-1 medications are a class of drugs that mimic a hormone called glucagon-like peptide-1, which helps regulate blood sugar and appetite

As GLP-1 receptor agonists transition from short-term interventions to long-term or indefinite therapy for many patients, understanding the implications of extended use becomes increasingly important

Pharmacist-led medication review at GLP-1 receptor agonist initiation: impact on drug interaction identification