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the bronchodilator ipratropium and the calcium channel blocker verapamil) have been proposed as substrates 19,20 , though these compounds, alongside a number of other cationic drugs, were shown to be poor substrates for OCTN2 21

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Critics have questioned its accuracy and reproducibility, expressing concerns that excessive reliance on algorithms might lead to a narrow or oversimplified understanding of the complexity inherent in Chinese medicine [673, 674]

Seveljevic-Jaran et al., 2006