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Daily administration of setmelanotide in these studies resulted in notable reductions in hunger and significant weight loss
Female rats demonstrated equivocal evidence of carcinogenic activity based on increased incidences of mononuclear cell leukemia at 0.8 times the maximum human daily dose (MHDD) of 4 grams/day, based on a body surface area comparison
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Despite the evident heterogeneity of the clinical manifestation in ASD, animal research allows consistent investigations of different aspects of the condition, from circuitry to cellular and molecular processes affected in autism
[DOI] [PubMed] [Google Scholar] 95.Oliveira G, Diogo L, Grazina M, et al
