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In the phase 2 dose-finding trial involving 706 participants, nausea rates varied dramatically by dose

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Women are at greater risk of thyroid disorders and may thus have a higher requirement for additional selenium, particularly in pregnancy

Pediatr Res 39:992998 Tuttle KR, Bruton JL, Perusek MC, Lancaster JL, Kopp DT, DeFronzo RA (1991) Effect of strict glycemic control on renal hemodynamic response to amino acids and renal enlargement in insulin-dependent diabetes mellitus

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