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doi:10.3389/fnins.2022.867704

Further, increased expressions of liver PPAR- (peroxisome proliferator-activated receptors), which plays a vital role in decreasing triglycerides [57]

One study noted 17 cytokines had a significant upward linear trend with the severity of ME/CFS: CCL11 (Eotaxin-1), CXCL1 (GRO), CXCL10 (IP-10), IFN (interferon)-y, interleukin (IL)-4, IL-5, IL-7, IL-12p70, IL-13, IL-17F, leptin, G-CSF, GM-CSF, LIF, NGF, SCF, and TGF- (231)

Cagrilintide has a half-life of about 78 days (roughly 159195 hours measured in a Phase 1b study), and tirzepatide about 5 days (approximately 120 hours)

& Crofford, L