29 patients had used 1 or more GLP-1 RAs
In the DURATION-8 trial, dapagliflozin as monotherapy and in combination with EX-QW showed trends favoring improvements in LFC, glucose and lipid metabolism, and liver fibrosis scores at the end of the study, but no significant statistical differences were observed
The briefing was held 1 day after the publication of a white paper authored by the Center for Medicine in the Public Interest that criticized the FDA for not doing enough to crack down on illegal GLP-1 compounding and provided recommendations calling for greater enforcement of existing FDA regulations
Moreover, GLP-1 may influence the composition and function of the gut microbiota, which plays a pivotal role in IBD pathogenesis [384]
People with diabetes and a history of retinopathy, particularly proliferative diabetic retinopathy, should be monitored closely, as rapid glucose reduction may temporarily worsen retinal conditions
Patients who value telehealth convenience but want medical monitoring, labs, and prescription delivery
