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The L-371,257 powder was dissolved in 10% dimethyl sulfoxide (DMSO) in phosphate buffered saline (PBS)

In preclinical models, inhibiting this receptor has been shown to mimic some of the physiological effects of endurance exercise

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24 patients with ME/CFS, 25 patients with long COVID and 24 healthy controls (HC) underwent brain (pregenual and dorsal anterior cingulate cortex, respectively, pgACC and dACC) and calf muscle MRS scanning at 7 Tesla, followed by a computerised cognitive assessment

Cusin, C