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When encountering elevated intracellular GSH levels, these metal-based complexes break down, triggering the targeted release of photosensitizers

Starting with lower doses helps identify individual tolerance levels

Figure 2A-B shows increased ROS in HO-treated IEC-6 cells, with SAC treatment reducing ROS levels compared to untreated cells

There is a lack of clinical trials investigating the effect of vitamin B12 supplementation on liver enzymes in NAFLD patients

20,21 The MDM2 binding area of the p53 TAD overlaps with some of the binding regions for p300, which is critical for the transcriptional function of p53

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