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Overexpression of MMPs can result to excessive ECM breakdown, contributing to the pathogenesis of various respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma, acute respiratory distress syndrome (ARDS) and pulmonary fibrosis [37,38,39,40]

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It is most effective when combined with healthier nutrition habits, increased physical activity, behavior changes, and regular medical follow-up

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Microbial population present in fermented beverage 'cauim' produced by Brazilian Amerindians

ASP2357 may often contribute to stabilizing interactions, enhancing the drugs specificity and affinity