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Although GLP-1 kind has been deeply studied, many GIP aspect fundamental features should be more clarified, such as an alanine scanning, to support development of GLP-1R/GIPR bifunctional drugs

Cardiac evaluation of function and myocardial scarring is non-invasively best supported by cardiac magnetic resonance imaging (CMR) with late gadolinium enhancement (LGE)

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Ferroptosis inducers have been studied to act directly on breast cancer cells to exert anticancer effects and also as sensitizers for radiotherapy to reverse tumor radiotherapy resistance

Phase 2 Trial Results (NEJM 2023) The landmark Phase 2 trial enrolled 338 adults with obesity (BMI 30) or overweight with comorbidities (BMI 27) but without diabetes