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It may even be linked to a wide range of clinical conditions including cancer and diabetes

Tirzepatide A first-in-class dual GIP/GLP-1 receptor agonist investigated for superior metabolic research applications, producing greater weight loss and glycemic control than selective GLP-1 agonists

Naltrexone, approved in 1984, introduced a non-opioid antagonist that blocked the effects of opioids but required full detoxification before initiation, limiting its early use

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Accessed 11/3/2020, Kerber KA