Supply chain: Compounded tirzepatide availability depends on the FDA shortage list
Based on clinically available variables (BMI, waist circumference, OGTT/HOMA-IR, lipid profiles, NAFLD assessments, androgens, SHBG, and ultrasound markers), interpretable risk stratification models should be established rather than replacing clinical logic with black-box algorithms (173, 174)
Long-term safety and efficacy of the sodium-glucose cotransporter 2 inhibitor, tofogliflozin, added on glucagon-like peptide-1 receptor agonist in Japanese patients with type 2 diabetes mellitus: a 52-week open-label, multicenter, post-marketing clinical study
J Biomol Struct Dyn 39(8):28382856 Pathak RK, Kim W, Kim J (2023) Targeting the PEDV 3CL protease for identification of small molecule inhibitors: an insight from virtual screening, ADMET prediction, molecular dynamics, free energy landscape, and binding energy calculations
Available at: (Accessed October 21, 2019)
For someone taking topiramate for seizure control or migraine prevention, this could potentially lead to a breakthrough symptom