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It is considered to be the final step in eukaryotic nitrogen excretion and very important in recycling oxidised NAD +

thaliana , the gene expression of GLR homolog3.5 (AtGLR3.5, constituting Ca 2+ channels) was significantly up-regulated in germinating seeds, which in turn increased cytosolic Ca 2+ concentration, eventually stimulating seed germination via counteracting the inhibiting effect of ABA (Kong et al., 2015)

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NAD's biological importance goes way beyond simple cellular functions