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Developing senolytics with high selectivity and efficacy in targeting senescent cells while minimizing off-target effects on healthy cells remains an ongoing challenge

However, whereas eNAP-1 is present only in very low quantities in equine neutrophils, eNAP-2 seems to be one of the major gene products [32]

Glutathione may interact with certain medications, including some chemotherapy drugs

10.1186/s12871-024-02737-w 27 OvenholmH.ZaighamS.FrantzS.NihlenU.WollmerP.HamreforsV

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Kaczmarek J.L., Liu X., Charron C.S., Novotny J.A., Jeffery E.H., Seifried H.E., Ross S.A., Miller M.J., Swanson K.S., Holscher H.D

AHK-Cu may also reduce the secretion of transforming growth factor-beta1 by dermal fibroblasts