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Metabolomic changes in the mouse retina after optic nerve injury

Third, the APR-017 and LCS3 induced increase in ROS, decrease in GSH, and inhibition of cell growth in VRK2-KO cells could be reversed by supplying a GSH compensator

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Following the observations that 5-oxoprolinase (OPLAH) knockdown have higher propensity for heart failure in mouse and man has brought the substrate of OPLAH, 5-oxoproline, into focus

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Further, good results can be achieved with the use of a microorganism, or esterase or protease, which has a hydrolytic capacity