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Conclusion Despite the new AAP guidelines, important considerations remain about the broader usage of pharmacotherapy and challenges of weight management in children and adolescents
Adipocyte hypertrophy is associated with increased uptake of excess TAGs, which triggers fat accumulation within the larger subcutaneous adipose tissue (SAT) [18, 19, 20]
Ratner RE, Maggs D, Nielsen LL, et al
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Peer review Peer review information Nature Reviews Nephrology thanks Beatriz Fernandez Fernandez, John He and Jun Wada for their contribution to the peer review of this work
