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The use of NNMT inhibitors as a potential obesity treatment has been investigated preclinically 8,9,13 , and observational clinical data suggests that increased NNMT expression and activity correlate with increased incidence of Type 2 diabetes (T2D) and risk of obesity, respectively 10,11

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However, research shows cortisone weakens tendon structure and may increase rupture risk with repeated injections

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injection, 750 mg/kg/day) 25,50 to the mice (Fig

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