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432/2012 permits the health claim that "olive oil polyphenols contribute to the protection of blood lipids from oxidative stress" only for oils containing at least 5 mg of hydroxytyrosol and its derivatives (including the oleuropein complex and tyrosol) per 20 g of oil -- equivalent to roughly 250 mg/kg

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(1) The team discovered it while studying sleep-promoting factors in the brain and when they injected the isolated fraction into recipient animals, those animals showed a rapid increase in delta wave (slow-wave) sleep