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However, IL-15-mediated upregulation of ZO-1 and ZO-2 expression was independent of the IL-2R subunit, whereas phosphorylation of occludin and enhanced membrane association of claudin-1 and claudin-2 by IL-15 required the presence of the IL-2R subunit

Under the GLP-1-RA therapy, patients lost on average two-thirds of the weight regained from their nadir weight

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