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Key points: Why Mounjaro causes headaches Dehydration is a common cause of headaches in people taking Mounjaro Blood sugar drops can trigger headaches, especially on an empty stomach Significantly reduced calorie intake may cause nutritional headaches Sleep disruption from medication side effects can trigger headaches Some headaches may relate to direct effects on brain pressure or blood vessels Most causes are preventable with simple lifestyle changes How common are headaches on Mounjaro

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