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both in conjunction with a reduced-calorie diet (~500 kcal/day deficit) and increased physical activity (recommended to a minimum of 150 min/week)

Different from the function of most tight junctions (such as occludin, claudin-1, ZO-1), the expression of claudin-2 protein increases the cell bypass permeability, leading to the destruction of the intestinal epithelial barrier and the increase in bacterial translocation and transmission, and then resulting intestinal dysbiosis [90, 91]

While your body needs potassium for your heart and muscles to work, too much of it can lead to serious heart rhythm problems or even cause the heart to stop

These medications carry a Black Box Warning for the potential risk of thyroid tumors

After battling her own health challenges during and after COVID, she discovered IV therapy as part of her recovery, and it changed everything

These limitations matter, and they are why the formal recommendation remains cautious