Ali said that through future research, it would be interesting to see if this improvement in kidney function through the use of semaglutide is independent of weight loss
However, patients with type 2 diabetes require alternative glycemic management strategies before discontinuation, and gradual transition to lifestyle-focused maintenance may optimize outcomes for all patients
Patients with genetic predispositions toward higher appetite drive (FTO variants) or altered GLP-1 receptor sensitivity may have different starting points for semaglutide dosing or tolerance profiles
Using 1:1 propensity matching, researchers compared 1,101 GLP-1 RA users with 1,101 non-users, matched by demographics, comorbidities, and medication history
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