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The supplement works by inhibiting tyrosinase activity and converting eumelanin (dark pigment) to pheomelanin (lighter pigment)

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However, as research continued, erythrocytes were shown to affect vascular tone, immunity, redox homeostasis, and blood clotting

These conventional therapies present challenges such as treatment cost, infection risk, poor patient compliance, organ rejection, availability issues, and the need for immunosuppressant drugs and frequent dialysis [223,224,225]

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