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Frequently Asked Questions Why do GLP-1 medications cause constipation

Constipation is listed among common reactions

Recent findings from the SELECT (short for semaglutide effects on heart disease and stroke in patients with overweight or obesity) trial suggest that semaglutide may slow the decline of kidney function and reduce albuminuria, though more research is needed to confirm its safety and efficacy in non-diabetic CKD patients, especially since a large subset in SELECT was low-risk and not fully treated with RAS inhibitors

Lab work helps establish your baseline health and checks for any red flags that could make GLP-1s unsafe

More if youre experiencing diarrhea or vomiting

The degraded peptide fragments do not simply become inactive