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Contraindications ZOFRAN is contraindicated in patients: known to have hypersensitivity (e.g., anaphylaxis) to ondansetron or any of the components of the formulation [see Adverse Reactions (6.2)] receiving concomitant apomorphine due to the risk of profound hypotension and loss of consciousness 5

Isotretinoin can cause significant fatigue and muscle soreness

Patients are encouraged to communicate openly with their healthcare providers about their pain levels and any concerns regarding their medication regimen

No human data exists on birth outcomes, organ development, or long-term effects on children exposed in utero

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