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Lycopene reduces hypertension in overweight/obese people [103]

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doi: 10.1097/MIB.0000000000000318 24 Feilstrecker BalaniG.Dos Santos CortezM.Picasky da Silveira FreitasJ

As further proof, we inhibited transketolase (non-oxPPP) activity by oxythiamine and observed a decrease in UMP m+2 labelling in both genotypes, but only WT chondrocytes showed an upregulation of UMP m+1 labelling, indicating that only WT cells could increase oxPPP activity as compensation (Extended Data Fig

Because its level in the blood is almost entirely dependent on the kidneys, it is a sensitive marker of renal function and is used to estimate GFR (Levey 1999)

For targets with no existing fluorophore conjugated antibody the following primary antibodies were used: anti NRF2 polyclonal (1:200, Thermofisher, PA5-27882)