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Various mechanisms have been theorized to describe how dual agonism, as GLP-1 RA, could directly reduce triglycerides hepatocyte storage, lipogenesis and improving hepatic glucose metabolism (96) and promoting lipolysis and fatty acid oxidation (97)
TGA, Therapeutic Goods Administration
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Reducing Appetite and Increasing Satiety: GLP-1 acts on receptors in the brain to reduce hunger signals, leading to decreased food intake and significant weight loss
Gut (1978) 19:1006 14
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