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There were no statistically significant differences observed between the two subgroups ( P = 0.06) (Additional file 2: Fig

Nausea rates ranged from 17% to 60% depending on the specific protocol arm, highlighting why titration speed matters enormously at this level

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The association of incretin-based therapy with thyroid cancer originates from preclinical data showing the elevation of calcitonin and occurrence of hyperplasia and tumors arising from rat thyroid gland parafollicular C cells after treatment with liraglutide, a GLP-1R agonist [18,19,20]

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While these approaches produce results, they come with significant costs, downtime, and in the case of surgery, inherent risks