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6,7 A disproportionate percentage of American Indian and Alaska Natives (AI/AN) use commercial tobacco compared to other ethnic groups in the United States

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9 While no single factor can reliably determine the risk of carcinoma, several have been highlighted as important predictive factors: Dysplasia grade The degree of dysplasia is regarded as the most important determinant for progression to invasive carcinoma, 10 with the risk of malignant transformation increasing with increasing degrees of OED