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RC and YY revised the final manuscript

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However, considering the impact of sex hormones, particularly estradiol, on lipid metabolism and cardiovascular health, it is essential to fully consider gender differences and the potential role of sex hormones when exploring the association between PFAS exposure and lipid parameters as well as AIP [52]

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An increase in body fat is associated with an excess amount of estrogen, which needs to be well-balanced in order to have a regular period schedule

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