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Some patients report improved energy levels as dietary patterns stabilize and blood glucose levels (in those with prediabetes or diabetes) improve

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PlexusDx also offers oral formulations of both compounds, along with GLP-Squared (a dual-compound injection combining semaglutide and tirzepatide) for patients who don't respond adequately to single-agent therapy

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Clinical trials report burping in approximately 1 to 3% of patients

Common Side Effects Local injection reactions: Pain, warmth, redness, itching or a transient flush at the site are the most commonly reported effects, consistent with any intramuscular injection