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Approach the issue with an open mindyour clinician can provide a recommendation after you discuss goals, side effect concerns, health history, and cost/accessibility

The short answer is that both medications can produce significant weight loss, but retatrutide appears to lead to greater average weight reduction in clinical studies because it targets three hormone receptors involved in metabolism rather than one

If pregnancy occurs while taking semaglutide, the medication should be discontinued immediately, and the healthcare provider should be notified

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In this analysis, 6-month weight change achieved among those randomized to WL was 7.7%(95% CI 8.3% to 7.2%), with no difference noted by sex