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Given the consistent selection of aKG and creatine across all the analytical approaches, their associations with demographic and clinical variables were further explored (Supplemental Tables S4 & S5)

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Combined melanocytic nevus can be distinguished from melanoma by the absence of melanoma in situ in the junctional component, lack of pleomorphism including a prominent nucleolus in tumor cells and expansile growth pattern in the dermal component, and by the absence of or only very occasional normal mitoses in combined nevus

so, curcumin nanoformulations can be effectively used to treat PC and other diseases [28]