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Chen JL, Weiss S, Heyman MB, Vittinghoff E, Lustig R: Pilot study of an individually tailored educational program by mail to promote healthy weight in Chinese-American children

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Retatrutide is currently undergoing large-scale Phase 3 clinical trials (the TRIUMPH program)

CJC-1295 is a synthetic analogue of Growth Hormone-Releasing Hormone (GHRH) with tetrasubstituted modifications (D-Ala, Gln, Ala, Leu) that protect the peptide from degradation by the enzyme DPP-IV, thereby extending its half-life relative to native GHRH

Heres how they compare at the maximum dose for each: Some things to note: Tirzepatide vs semaglutide: At the maximum dosage of tirzepatide, lower nausea, vomiting, diarrhea, and constipation rates have been reported compared to the highest dose of semaglutide