However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007
AOD 9604 is a synthetic fragment of human growth hormone, specifically amino acids 176 through 191 of the hGH sequence, with a single modification at the N-terminus for stability
The most common adverse events were mild-to-moderate headaches, similar in frequency to placebo groups
Growth hormone and its derivatives have maximum fat-burning effects when insulin is low and glucagon is elevated - which happens during fasting
Both CJC 1295 and ipamorelin mimic the action of growth hormone-releasing hormone (GHRH), and in turn, stimulate the release of growth hormone (GH) from the anterior pituitary gland
AOD 9604 is not a rapid intervention