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Left Ventricular Function : Obesity can lead to left ventricular hypertrophy and impaired cardiac function

To study the permeability of nanoparticles in vitro BBB models, which conform to the 3R principles with the minimalization the number of animal experiments, are widely used either in static [34] or in dynamic conditions by employing lab-on-a-chip systems [35]

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In the six simulations, the first principal component accounted for between 35% and 50% of the total variance, while none of the remaining components contributed more than 15%

doi: 10.1016/j.phymed.2021.153544 101