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A GLP-1 plateau occurs when a patients weight loss or metabolic progress slows dramatically or stops altogether , despite continued medication use

Lawsuits now pending around the country allege that patients developed severe vision problems after using these medications and were not adequately warned about the risk

doi: 10.1021/jacsau.2c00130 de Bray A, Roberts AG, Armour S, Tong J, Huhn C, Gatin-Fraudet B, Romann K, Shilleh AH, Jiang W, Figueredo Burgos NS, Trott JPP, Viloria K, Nasteska D, Pearce A, Miyazaki S, Tomlinson JW, Owen DM, Nieves DJ, Ast J, Cyranka M, Epanchintsev A, mml C, Reimann F, Soykan T, Ladds G, Adriaenssens AE, Trapp S, Jones B, Broichhagen J, Hodson DJ

72 Bone loss is influenced by initial body weight, age, sex, physical activity, extent of energy restriction and protein intake, and rate of weight reduction, with older individuals and females experiencing greater bone loss

For patients who have resolved their diabetes using a GLP-1 for weight loss and glucose control, they may have a return of their type 2 diabetes, says Lofton, who adds that it varies from person to person

doi: 10.1056/NEJMoa1916038 98 PetriKCCIngwersenSHFlintAZachoJOvergaardRV