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By inhibiting NNMT, 5Amino1MQ Peptide reshapes the metabolic phenotype of adipose tissue, promotes lipolysis, increases energy expenditure, and restores dynamic balance of fat metabolism - one of its core weightloss mechanisms

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Furthermore, the administration of isoliquiritigenin reversed the downregulation of mitochondrial biogenesis-related proteins, including Nrf2, HO-1, Sirt1 and PGC1-, in human chondrocytes